Paul Ritter: Automated generation of reconstructive tissue scaffolds
A promising approach to reconstruct human muscle tissue after trauma, necrosis or tumor ablation is the use of cell-free muscle scaffolds processed from previously intact donor organs. Up to now, the required chemical decellularization of tissues is performed mostly manually, with predefined incubation times.
Recently, Paul Ritter developed a novel bioreactor system. It provides automated and standardized generation of these acellular muscle scaffolds, and is capable of monitoring and adjusting the progress on-the-fly. In his publication “MyoBio: An Automated Bioreactor System Technology for Standardized Perfusion-Decellularization of Whole Skeletal Muscle”, Paul describes the versatility and future potential of the system. It may be an important advancement for providing new bioartificial tissue for reconstructive surgery.